Assay Detail
Binding
CHEMBL4229697
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of MASP-2-mediated C4 deposition in human serum after 1 hr by ELISA
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Target
Mannan-binding lectin serine protease 2 (CHEMBL4295646) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Chemical Approaches to Modulating Complement-Mediated Diseases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.11 | 6.64 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4240381 | — | — | 1 | 6.64 |
| CHEMBL4246684 | — | — | 1 | 5.57 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4240381 | — | IC50 | = | 230.0 | nM | 6.64 |
| CHEMBL4246684 | — | IC50 | = | 2700.0 | nM | 5.57 |