Assay Detail
Binding
CHEMBL4229706
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of C9 binding to C5b678 in zymogen activated human serum assessed as suppression of human erythrocyte lysis after 1 hr by ELISA
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Publication
Chemical Approaches to Modulating Complement-Mediated Diseases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.30 | 6.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4238111 | — | — | 1 | 6.30 |
| CHEMBL4242254 | — | — | 1 | 6.30 |
| CHEMBL275938 | AURINTRICARBOXYLIC ACID | — | 1 | 6.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4238111 | — | IC50 | = | 500.0 | nM | 6.30 |
| CHEMBL4242254 | — | IC50 | = | 500.0 | nM | 6.30 |
| CHEMBL275938 | AURINTRICARBOXYLIC ACID | IC50 | = | 500.0 | nM | 6.30 |