Assay Detail
Binding
CHEMBL4229754
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of recombinant HIV protease expressed in inclusion bodies of Escherichia coli BL21 (DE3)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Human immunodeficiency virus |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Publication
Quest for Novel Chemical Entities through Incorporation of Silicon in Drug Scaffolds.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 9.43 | 9.43 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL109952 | — | — | 1 | 9.43 |
| CHEMBL5483011 | INDINAVIR | 3.0 | 1 | 9.42 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL109952 | — | Ki | = | 0.37 | nM | 9.43 |
| CHEMBL5483011 | INDINAVIR | Ki | = | 0.38 | nM | 9.42 |