Assay Detail
Binding
CHEMBL4232355
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of cyclooxygenase-1 in rat RBL-1 cells preincubated for 10 mins followed by [14C]arachidonic acid addition and measured after 5 mins by radioligand binding assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Cell Type | RBL-1 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Benzopyrroloxazines containing a bridgehead nitrogen atom as promising scaffolds for the achievement of biologically active agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 5.82 | 5.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL61422 | — | — | 1 | 5.82 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL61422 | — | IC50 | = | 1500.0 | nM | 5.82 |