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Assay Detail

CHEMBL4233270

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ADMET
Antiproliferative activity against mouse BALB/3T3 cells after 72 hrs by MTT assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type ADMET
Organism Mus musculus
Cell Type BALB/3T3
Confidence 1 — Organism
Curated By Intermediate

Target

BALB/3T3 (CHEMBL613876)
Type CELL-LINE
Organism Mus musculus

Publication

Phosphorus-containing isothiocyanate-derived mercapturic acids as a useful alternative for parental isothiocyanates in experimental oncology.
Psurski M, Janczewski Ł, Świtalska M, Gajda A, Goszczyński TM, Ciekot J, Winiarski Ł, Oleksyszyn J, Wietrzyk J, Gajda T.
Bioorg Med Chem Lett (2018) 28 : 2611 -2615
PubMed 29945793 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.03 5.10

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4246861 1 5.10
CHEMBL4248286 1 4.96

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4246861 IC50 = 7900.0 nM 5.10
CHEMBL4248286 IC50 = 10900.0 nM 4.96