Assay Detail
Functional
CHEMBL4233273
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Antiproliferative activity against human MES-SA/Dx5 cells after 72 hrs by SRB assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MES-SA/Dx5 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Phosphorus-containing isothiocyanate-derived mercapturic acids as a useful alternative for parental isothiocyanates in experimental oncology.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.12 | 5.58 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4246861 | — | — | 1 | 5.58 |
| CHEMBL4248286 | — | — | 1 | 4.99 |
| CHEMBL53463 | DOXORUBICIN | 4.0 | 1 | 4.79 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4246861 | — | IC50 | = | 2600.0 | nM | 5.58 |
| CHEMBL4248286 | — | IC50 | = | 10300.0 | nM | 4.99 |
| CHEMBL53463 | DOXORUBICIN | IC50 | = | 16200.0 | nM | 4.79 |