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Assay Detail

CHEMBL4234450

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of horseradish peroxidase by oxalate detection based assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Armoracia rusticana
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Salicylic Acid Derivatives Inhibit Oxalate Production in Mouse Hepatocytes with Primary Hyperoxaluria Type 1.
Moya-Garzón MD, Martín Higueras C, Peñalver P, Romera M, Fernandes MX, Franco-Montalbán F, Gómez-Vidal JA, Salido E, Díaz-Gavilán M.
J Med Chem (2018) 61 : 7144 -7167
PubMed 30028141 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.75 4.75

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4237565 1 4.75

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4237565 IC50 = 18000.0 nM 4.75