Assay Detail
Functional
CHEMBL4234775
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Antimalarial activity against erythrocytic stage of synchronized Plasmodium falciparum Dd2 after 48 hrs by Picogreen dye based fluorescence assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Antiprotozoal and cysteine proteases inhibitory activity of dipeptidyl enoates.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.07 | 5.79 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4245127 | — | — | 1 | 5.79 |
| CHEMBL4242138 | — | — | 1 | 5.17 |
| CHEMBL4244656 | — | — | 1 | 4.83 |
| CHEMBL4251480 | — | — | 1 | 4.79 |
| CHEMBL4249696 | — | — | 1 | 4.75 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4245127 | — | IC50 | = | 1610.0 | nM | 5.79 |
| CHEMBL4242138 | — | IC50 | = | 6810.0 | nM | 5.17 |
| CHEMBL4244656 | — | IC50 | = | 14940.0 | nM | 4.83 |
| CHEMBL4251480 | — | IC50 | = | 16080.0 | nM | 4.79 |
| CHEMBL4249696 | — | IC50 | = | 17740.0 | nM | 4.75 |