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Assay Detail

CHEMBL4234923

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Vasorelaxant activity in Wistar rat endothelium-denuded 3rd-order mesenteric artery assessed as reduction in norepinephrine-induced vessel contraction by myographic method
2
Total Activities
1
Compounds Tested
2
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Rattus norvegicus
Tissue Artery
Confidence 1 — Organism
Curated By Intermediate

Target

Artery (CHEMBL4296528)
Type TISSUE
Organism Rattus norvegicus

Publication

Terpenoids with vasorelaxant effects from the Chinese liverwort Scapania carinthiaca.
Qiao Y, Zheng H, Li L, Zhang J, Li Y, Li S, Zhu R, Zhou J, Zhao S, Jiang Y, Lou H.
Bioorg Med Chem (2018) 26 : 4320 -4328
PubMed 30049584 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
%max 1 - -
EC50 1 4.43 4.43

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4246908 2 4.43

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4246908 EC50 = 37000.0 nM 4.43
CHEMBL4246908 %max = 20.0 % -