Assay Detail
Functional
CHEMBL4235134
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Antiproliferative activity against human MDA-MB-231 cells after 24 hrs by SYBR green dye based fluorescence assay
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MDA-MB-231 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Novel tertiary sulfonamides as potent anti-cancer agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 10 | 7.62 | 7.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4248974 | — | — | 1 | 7.89 |
| CHEMBL4240141 | — | — | 1 | 7.89 |
| CHEMBL4238053 | — | — | 1 | 7.85 |
| CHEMBL4240212 | — | — | 1 | 7.82 |
| CHEMBL4244338 | — | — | 1 | 7.80 |
| CHEMBL4246320 | — | — | 1 | 7.77 |
| CHEMBL4243509 | — | — | 1 | 7.70 |
| CHEMBL4240977 | — | — | 1 | 6.22 |
| CHEMBL4243377 | — | — | 1 | - |
| CHEMBL4243580 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4248974 | — | IC50 | = | 13.0 | nM | 7.89 |
| CHEMBL4240141 | — | IC50 | = | 13.0 | nM | 7.89 |
| CHEMBL4238053 | — | IC50 | = | 14.0 | nM | 7.85 |
| CHEMBL4240212 | — | IC50 | = | 15.0 | nM | 7.82 |
| CHEMBL4244338 | — | IC50 | = | 16.0 | nM | 7.80 |
| CHEMBL4246320 | — | IC50 | = | 17.0 | nM | 7.77 |
| CHEMBL4243509 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4240977 | — | IC50 | = | 608.0 | nM | 6.22 |
| CHEMBL4243377 | — | IC50 | > | 5000.0 | nM | - |
| CHEMBL4243580 | — | IC50 | > | 5000.0 | nM | - |