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Assay Detail

CHEMBL4235455

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against Influenza A virus (A/Puerto Rico/8/1934(H1N1)) infected in MDCK cells after 24 hrs by immunofocus assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Influenza A virus
Cell Type MDCK
Confidence 1 — Organism
Curated By Intermediate

Target

Influenza A virus (CHEMBL613740)
Type ORGANISM
Organism Influenza A virus

Publication

Identification of influenza PA-Nter endonuclease inhibitors using pharmacophore- and docking-based virtual screening.
Ferro S, Gitto R, Buemi MR, Karamanou S, Stevaert A, Naesens L, De Luca L.
Bioorg Med Chem (2018) 26 : 4544 -4550
PubMed 30082105 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 4.94 4.94

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2443239 1 4.94

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2443239 EC50 = 11400.0 nM 4.94