Assay Detail
Functional
CHEMBL4254149
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Cytotoxicity against human PC3 cells assessed as reduction in cell viability after 72 hrs by MTT assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | PC-3 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and anticancer activity of novel water soluble benzimidazole carbamates.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 5.88 | 5.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL685 | MEBENDAZOLE | 4.0 | 1 | 5.96 |
| CHEMBL4288184 | — | — | 1 | 5.80 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL685 | MEBENDAZOLE | EC50 | = | 1100.0 | nM | 5.96 |
| CHEMBL4288184 | — | EC50 | = | 1600.0 | nM | 5.80 |