Assay Detail
Binding
CHEMBL4254483
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of soybean 15-LOX using linoleic acid as substrate by colorimetric method
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Glycine max |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Novel click modifiable thioquinazolinones as anti-inflammatory agents: Design, synthesis, biological evaluation and docking study.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 5.32 | 5.62 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL93 | ZILEUTON | 4.0 | 1 | 5.62 |
| CHEMBL4279346 | — | — | 1 | 5.40 |
| CHEMBL4285920 | — | — | 1 | 5.36 |
| CHEMBL4290032 | — | — | 1 | 5.28 |
| CHEMBL1562610 | MECLOFENAMATE SODIUM | 4.0 | 1 | 5.25 |
| CHEMBL4289748 | — | — | 1 | 5.21 |
| CHEMBL4279764 | — | — | 1 | 5.12 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL93 | ZILEUTON | IC50 | = | 2410.0 | nM | 5.62 |
| CHEMBL4279346 | — | IC50 | = | 3980.0 | nM | 5.40 |
| CHEMBL4285920 | — | IC50 | = | 4330.0 | nM | 5.36 |
| CHEMBL4290032 | — | IC50 | = | 5210.0 | nM | 5.28 |
| CHEMBL1562610 | MECLOFENAMATE SODIUM | IC50 | = | 5640.0 | nM | 5.25 |
| CHEMBL4289748 | — | IC50 | = | 6210.0 | nM | 5.21 |
| CHEMBL4279764 | — | IC50 | = | 7620.0 | nM | 5.12 |