Assay Detail
Binding
CHEMBL4255076
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Inhibition of yeast 20S immunoproteasome beta-5
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Saccharomyces cerevisiae |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Structure-based design of human immuno- and constitutive proteasomes inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.83 | 5.14 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4293405 | — | — | 1 | 5.14 |
| CHEMBL2337850 | — | — | 1 | 4.89 |
| CHEMBL4286415 | — | — | 1 | 4.47 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4293405 | — | IC50 | = | 7300.0 | nM | 5.14 |
| CHEMBL2337850 | — | IC50 | = | 13000.0 | nM | 4.89 |
| CHEMBL4286415 | — | IC50 | = | 34000.0 | nM | 4.47 |