Assay Detail
Binding
CHEMBL4256036
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of full length human recombinant C-terminal His-tagged HDAC2 expressed in baculovirus infected Sf9 insect cells using substrate after 90 mins by colorimetric method
3
Total Activities
3
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | Sf9 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Elimination of HIV-1 Latently Infected Cells by Gnidimacrin and a Selective HDAC Inhibitor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Inhibition | 2 | - | - |
| IC50 | 1 | 7.16 | 7.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL235842 | — | — | 1 | 7.16 |
| CHEMBL4282815 | — | — | 1 | - |
| CHEMBL3622374 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL235842 | — | IC50 | = | 70.0 | nM | 7.16 |
| CHEMBL4282815 | — | Inhibition | - | % | - | |
| CHEMBL3622374 | — | Inhibition | - | % | - |