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Assay Detail

CHEMBL4256048

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of porcine pancreatic lipase
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Sus scrofa
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Pancreatic triacylglycerol lipase (CHEMBL1687677)
Type SINGLE PROTEIN
Organism Sus scrofa

Publication

Stereochemical Structure Activity Relationship Studies (S-SAR) of Tetrahydrolipstatin.
Liu X, Wang Y, Duclos RI, O'Doherty GA.
ACS Med Chem Lett (2018) 9 : 274 -278
PubMed 29541373 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.82 7.82

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4291122 1 7.82

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4291122 IC50 = 15.0 nM 7.82