Assay Detail
Functional
CHEMBL4256372
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Cytotoxicity against human MCF7 cells after 24 hrs by annexin-V-FITC/propidium iodide staining based flow cytometric method
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MCF7 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
New Hybrids Derived from Podophyllic Aldehyde and Diterpenylhydroquinones with Selectivity toward Osteosarcoma Cells.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 4.52 | 4.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL23741 | — | — | 1 | 4.52 |
| CHEMBL4282812 | — | — | 1 | - |
| CHEMBL61 | PODOFILOX | 4.0 | 1 | - |
| CHEMBL309880 | PODOPHYLLIC ALDEHYDE | — | 1 | - |
| CHEMBL4279359 | — | — | 1 | - |
| CHEMBL4284818 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL23741 | — | IC50 | = | 29900.0 | nM | 4.52 |
| CHEMBL4282812 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL61 | PODOFILOX | IC50 | > | 100000.0 | nM | - |
| CHEMBL309880 | PODOPHYLLIC ALDEHYDE | IC50 | > | 100000.0 | nM | - |
| CHEMBL4279359 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL4284818 | — | IC50 | > | 100000.0 | nM | - |