Assay Detail

CHEMBL4256570

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Functional

Cytotoxicity against human HPBALL cells after 72 hrs by alamar blue dye based fluorescence assay

ChEMBL ↗

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Target

HPBALL (CHEMBL4296435) ↗

Open DB target context

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Primary target HPBALL

CHEMBL4296435

Anchored from Assay target.

Protein identity HPBALL

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Homo sapiens
Cell Type	HPBALL
Confidence	1 — Organism
Curated By	Intermediate

Target

HPBALL (CHEMBL4296435) ↗

Type	CELL-LINE
Organism	Homo sapiens

Publication

The Notch Inhibitors Isolated from Nerium indicum.

Arai MA, Akamine R, Hayashi N, Koyano T, Kowithayakorn T, Ishibashi M.
J Nat Prod (2018) 81 : 1235 -1240
PubMed 29693393 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	7.85	7.85

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL4285883	OLEANDRIN	1.0	1	7.85

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL4285883	OLEANDRIN	IC50	=	14.0	nM	7.85