Assay Detail
Binding
CHEMBL4257239
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of mouse Eya3 catalytic domain (223 to 510 residues) by p-nitrophenylphosphate assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Publication
Use of small molecule inhibitors targeting eya tyrosine phosphatase
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.89 | 5.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1523279 | — | — | 1 | 5.00 |
| CHEMBL388590 | BENZBROMARONE | 4.0 | 1 | 4.96 |
| CHEMBL1474963 | BENZARONE | 4.0 | 1 | 4.72 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1523279 | — | IC50 | = | 10100.0 | nM | 5.00 |
| CHEMBL388590 | BENZBROMARONE | IC50 | = | 11000.0 | nM | 4.96 |
| CHEMBL1474963 | BENZARONE | IC50 | = | 19200.0 | nM | 4.72 |