Assay Detail
Binding
CHEMBL4257699
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of rat NaV1.3 by electrophysiological method
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Sodium channel protein type 3 subunit alpha (CHEMBL4966) ↗| Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
Publication
The discovery of a potent Na<sub>v</sub>1.3 inhibitor with good oral pharmacokinetics.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 8.22 | 8.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3617053 | — | — | 1 | 8.22 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3617053 | — | IC50 | = | 6.0 | nM | 8.22 |