Assay Detail
Binding
CHEMBL4258184
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Mycobacterium tuberculosis ICL1
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mycobacterium tuberculosis |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Target
Isocitrate lyase 1 (CHEMBL4295587) ↗| Type | SINGLE PROTEIN |
| Organism | Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) |
Publication
Development of NMR and thermal shift assays for the evaluation of <i>Mycobacterium tuberculosis</i> isocitrate lyase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 4.51 | 4.51 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4226192 | — | — | 1 | 4.51 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4226192 | — | IC50 | = | 30900.0 | nM | 4.51 |