Assay Detail
Functional
CHEMBL4258434
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antioxidant activity assessed as DPPH free radical scavenging after 10 mins by UV-vis spectrophotometric analysis
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Antiproliferative activity of novel isatinyl/indanyl nitrones (INs) as potential spin trapping agents of free radical intermediates.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 9 | 5.86 | 6.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4283253 | — | — | 1 | 6.22 |
| CHEMBL4276765 | — | — | 1 | 6.00 |
| CHEMBL4293824 | — | — | 1 | 5.92 |
| CHEMBL4279369 | — | — | 1 | 5.92 |
| CHEMBL4287418 | — | — | 1 | 5.89 |
| CHEMBL4287692 | — | — | 1 | 5.89 |
| CHEMBL4279790 | — | — | 1 | 5.75 |
| CHEMBL4291109 | — | — | 1 | 5.75 |
| CHEMBL146 | BUTYLATED HYDROXYTOLUENE | 2.0 | 1 | 5.42 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4283253 | — | EC50 | = | 600.0 | nM | 6.22 |
| CHEMBL4276765 | — | EC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL4293824 | — | EC50 | = | 1200.0 | nM | 5.92 |
| CHEMBL4279369 | — | EC50 | = | 1200.0 | nM | 5.92 |
| CHEMBL4287418 | — | EC50 | = | 1300.0 | nM | 5.89 |
| CHEMBL4287692 | — | EC50 | = | 1300.0 | nM | 5.89 |
| CHEMBL4279790 | — | EC50 | = | 1800.0 | nM | 5.75 |
| CHEMBL4291109 | — | EC50 | = | 1800.0 | nM | 5.75 |
| CHEMBL146 | BUTYLATED HYDROXYTOLUENE | EC50 | = | 3800.0 | nM | 5.42 |