Assay Detail
Binding
CHEMBL4258740
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [125I]-HEAT from human adrenergic alpha1A receptor expressed in rat-1 cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Synthesis and evaluation of nuciferine and roemerine enantiomers as 5-HT<sub>2</sub> and α<sub>1</sub> receptor antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 1 | 6.60 | 6.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL483825 | — | — | 1 | 6.60 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL483825 | — | Ki | = | 251.19 | nM | 6.60 |