Assay Detail
Functional
CHEMBL4259463
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Antiproliferative activity against human HeLa cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HeLa |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Chemical probes of Skp2-mediated p27 ubiquitylation and degradation.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.95 | 6.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL64894 | GENTIAN VIOLET | 4.0 | 1 | 6.40 |
| CHEMBL4291503 | — | — | 1 | 5.50 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL64894 | GENTIAN VIOLET | IC50 | = | 400.0 | nM | 6.40 |
| CHEMBL4291503 | — | IC50 | = | 3200.0 | nM | 5.50 |