Assay Detail
Functional
CHEMBL4261704
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Cytotoxicity against human UM-UC-3 cells assessed as decrease in cell viability after 72 hrs by CCK8 assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | UMUC3 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Development of small molecular compounds targeting cancer stem cells.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.87 | 8.24 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3672295 | — | — | 1 | 8.24 |
| CHEMBL3672369 | — | — | 1 | 7.50 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3672295 | — | IC50 | = | 5.7 | nM | 8.24 |
| CHEMBL3672369 | — | IC50 | = | 32.0 | nM | 7.50 |