Assay Detail
Binding
CHEMBL4261716
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of full length N-terminal GST-fused human PBK expressed in baculovirus expression system using FITC-labeled histone H3 peptide as substrate after 1 hr by IMAP method
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Lymphokine-activated killer T-cell-originated protein kinase (CHEMBL4896) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Development of small molecular compounds targeting cancer stem cells.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 8.07 | 8.59 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3672295 | — | — | 1 | 8.59 |
| CHEMBL3672369 | — | — | 1 | 7.55 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3672295 | — | IC50 | = | 2.6 | nM | 8.59 |
| CHEMBL3672369 | — | IC50 | = | 28.0 | nM | 7.55 |