Assay Detail
Functional
CHEMBL4263529
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antileishmanial activity against Leishmania braziliensis H3227 MHOM/BR/94/H-3227 promastigotes after 72 hrs by MTT assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Leishmania braziliensis |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Natural products as inhibitors of Leishmania major dihydroorotate dehydrogenase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.98 | 5.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL516873 | — | — | 1 | 5.22 |
| CHEMBL463060 | TAGITININ C | — | 1 | 5.04 |
| CHEMBL518700 | TAGITININ A | — | 1 | 4.69 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL516873 | — | IC50 | = | 6000.0 | nM | 5.22 |
| CHEMBL463060 | TAGITININ C | IC50 | = | 9200.0 | nM | 5.04 |
| CHEMBL518700 | TAGITININ A | IC50 | = | 20400.0 | nM | 4.69 |