Assay Detail
Functional
CHEMBL4263544
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antileishmanial activity against Leishmania amazonensis WHOM/BR/75/Josefa amastigotes after 72 hrs by Neubauer chamber method
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Leishmania amazonensis |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Natural products as inhibitors of Leishmania major dihydroorotate dehydrogenase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.63 | 4.93 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL489140 | KAURENOIC ACID | — | 1 | 4.93 |
| CHEMBL4285668 | — | — | 1 | 4.32 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL489140 | KAURENOIC ACID | IC50 | = | 11660.0 | nM | 4.93 |
| CHEMBL4285668 | — | IC50 | = | 47400.0 | nM | 4.32 |