Assay Detail
Functional
CHEMBL4263555
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antileishmanial activity against Leishmania amazonensis MHOM/77BR/LTB0016 promastigotes after 72 hrs by MTT assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Leishmania amazonensis |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Natural products as inhibitors of Leishmania major dihydroorotate dehydrogenase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.53 | 5.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL32749 | FERULATE | -1.0 | 1 | 5.77 |
| CHEMBL145 | CAFFEIC ACID | 3.0 | 1 | 5.28 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL32749 | FERULATE | IC50 | = | 1700.0 | nM | 5.77 |
| CHEMBL145 | CAFFEIC ACID | IC50 | = | 5200.0 | nM | 5.28 |