Assay Detail
Functional
CHEMBL4264676
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Antiproliferative activity against human HeLa cells after 72 hrs by CCK8 assay
14
Total Activities
14
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HeLa |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Design, synthesis and biological evaluation of novel carbamodithioates as anti-proliferative agents against human cancer cells.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 14 | 4.23 | 4.33 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4286592 | — | — | 1 | 4.33 |
| CHEMBL4285734 | — | — | 1 | 4.32 |
| CHEMBL4278671 | — | — | 1 | 4.31 |
| CHEMBL4282429 | — | — | 1 | 4.30 |
| CHEMBL4294984 | — | — | 1 | 4.29 |
| CHEMBL4277904 | — | — | 1 | 4.27 |
| CHEMBL4293808 | — | — | 1 | 4.23 |
| CHEMBL4283228 | — | — | 1 | 4.22 |
| CHEMBL4287198 | — | — | 1 | 4.21 |
| CHEMBL4285834 | — | — | 1 | 4.20 |
| CHEMBL48802 | SULFORAPHANE | 3.0 | 1 | 4.18 |
| CHEMBL4294424 | — | — | 1 | 4.16 |
| CHEMBL4279277 | — | — | 1 | 4.14 |
| CHEMBL49659 | — | — | 1 | 4.07 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4286592 | — | IC50 | = | 47290.0 | nM | 4.33 |
| CHEMBL4285734 | — | IC50 | = | 48230.0 | nM | 4.32 |
| CHEMBL4278671 | — | IC50 | = | 48650.0 | nM | 4.31 |
| CHEMBL4282429 | — | IC50 | = | 50500.0 | nM | 4.30 |
| CHEMBL4294984 | — | IC50 | = | 51000.0 | nM | 4.29 |
| CHEMBL4277904 | — | IC50 | = | 53390.0 | nM | 4.27 |
| CHEMBL4293808 | — | IC50 | = | 59410.0 | nM | 4.23 |
| CHEMBL4283228 | — | IC50 | = | 60530.0 | nM | 4.22 |
| CHEMBL4287198 | — | IC50 | = | 62430.0 | nM | 4.21 |
| CHEMBL4285834 | — | IC50 | = | 62680.0 | nM | 4.20 |
| CHEMBL48802 | SULFORAPHANE | IC50 | = | 66090.0 | nM | 4.18 |
| CHEMBL4294424 | — | IC50 | = | 69610.0 | nM | 4.16 |
| CHEMBL4279277 | — | IC50 | = | 73020.0 | nM | 4.14 |
| CHEMBL49659 | — | IC50 | = | 85050.0 | nM | 4.07 |