Assay Detail
Binding
CHEMBL4265139
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Inhibition of Streptococcus pneumoniae NanA using Neu5Acalpha2-3GalbetapNP as substrate after 30 mins by colorimetric assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Streptococcus pneumoniae |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Triazole-linked transition state analogs as selective inhibitors against V. cholerae sialidase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 4.31 | 5.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL96712 | NEU5AC2EN | — | 1 | 5.00 |
| CHEMBL1289311 | — | — | 1 | 4.35 |
| CHEMBL4289476 | — | — | 1 | 4.18 |
| CHEMBL4282280 | — | — | 1 | 4.00 |
| CHEMBL4278803 | — | — | 1 | 4.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL96712 | NEU5AC2EN | IC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL1289311 | — | IC50 | = | 44300.0 | nM | 4.35 |
| CHEMBL4289476 | — | IC50 | = | 65600.0 | nM | 4.18 |
| CHEMBL4282280 | — | IC50 | = | 100000.0 | nM | 4.00 |
| CHEMBL4278803 | — | IC50 | = | 100000.0 | nM | 4.00 |