Assay Detail
Binding
CHEMBL4265589
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of HER4 (unknown origin) in presence of 1 mM ATP concentration
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Receptor tyrosine-protein kinase erbB-4 (CHEMBL3009) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Identification of Cyanamide-Based Janus Kinase 3 (JAK3) Covalent Inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.45 | 5.45 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4292341 | — | — | 1 | 5.45 |
| CHEMBL4281393 | — | — | 1 | - |
| CHEMBL4277610 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4292341 | — | IC50 | = | 3540.0 | nM | 5.45 |
| CHEMBL4281393 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL4277610 | — | IC50 | > | 10000.0 | nM | - |