Assay Detail
Functional
CHEMBL4265682
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Antiproliferative activity against human A498 cells after 72 hrs by MTT assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | A498 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and in vitro antitumor activity of novel alkenyl derivatives of pyridoxine, bioisosteric analogs of feruloyl methane.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.06 | 5.21 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL53463 | DOXORUBICIN | 4.0 | 1 | 5.21 |
| CHEMBL4295033 | — | — | 1 | 5.19 |
| CHEMBL4292030 | — | — | 1 | 4.77 |
| CHEMBL106509 | DEHYDROZINGERONE | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL53463 | DOXORUBICIN | IC50 | = | 6100.0 | nM | 5.21 |
| CHEMBL4295033 | — | IC50 | = | 6500.0 | nM | 5.19 |
| CHEMBL4292030 | — | IC50 | = | 17000.0 | nM | 4.77 |
| CHEMBL106509 | DEHYDROZINGERONE | IC50 | = | 125000.0 | nM | - |