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Assay Detail

CHEMBL4267478

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiproliferative activity against human IMR32 cells after 72 hrs by XTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type IMR-32
Confidence 1 — Organism
Curated By Intermediate

Target

IMR-32 (CHEMBL614585)
Type CELL-LINE
Organism Homo sapiens

Publication

Role of p53 circuitry in tumorigenesis: A brief review.
Niazi S, Purohit M, Niazi JH.
Eur J Med Chem (2018) 158 : 7 -24
PubMed 30199707 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.28 7.28

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4279669 1 7.28

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4279669 IC50 = 52.6 nM 7.28