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Assay Detail

CHEMBL4269171

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Agonist activity at PPARalpha (unknown origin)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Peroxisome proliferator-activated receptor alpha (CHEMBL239)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Design, synthesis, and biological evaluation of novel pan agonists of FFA1, PPARγ and PPARδ.
Li Z, Zhou Z, Deng F, Li Y, Zhang D, Zhang L.
Eur J Med Chem (2018) 159 : 267 -276
PubMed 30296685 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 8.22 8.22

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL21241 GW7647 1 8.22

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL21241 GW7647 EC50 = 6.0 nM 8.22