Assay Detail
Functional
CHEMBL4269844
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against human 786-O cells assessed as decrease in cell viability after 72 hrs by MTS assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | 786-0 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Cyanobufalins: Cardioactive Toxins from Cyanobacterial Blooms.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 7.95 | 8.64 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4282477 | — | — | 1 | 8.64 |
| CHEMBL4293082 | — | — | 1 | 8.59 |
| CHEMBL399680 | BUFALIN | — | 1 | 8.12 |
| CHEMBL4282960 | — | — | 1 | 6.46 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4282477 | — | EC50 | = | 2.3 | nM | 8.64 |
| CHEMBL4293082 | — | EC50 | = | 2.6 | nM | 8.59 |
| CHEMBL399680 | BUFALIN | EC50 | = | 7.5 | nM | 8.12 |
| CHEMBL4282960 | — | EC50 | = | 350.0 | nM | 6.46 |