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Assay Detail

CHEMBL4269983

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of Staphylococcus aureus USA300 GFP-fused SaeRS after 8 hrs by fluorescence-based assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Staphylococcus aureus subsp. aureus USA300
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Total Synthesis of Xanthoangelol B and Its Various Fragments: Toward Inhibition of Virulence Factor Production of Staphylococcus aureus.
Mizar P, Arya R, Kim T, Cha S, Ryu KS, Yeo WS, Bae T, Kim DW, Park KH, Kim KK, Lee SS.
J Med Chem (2018) 61 : 10473 -10487
PubMed 30388007 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.53 5.68

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL494082 XANTHOANGELOL B 1 5.68
CHEMBL4286992 1 5.37

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL494082 XANTHOANGELOL B IC50 = 2100.0 nM 5.68
CHEMBL4286992 IC50 = 4300.0 nM 5.37