Assay Detail
Functional
CHEMBL4271249
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Cytotoxicity in human Caco2 cells after 72 hrs by MTT assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | Caco-2 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Recent discoveries of anticancer flavonoids.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 4.50 | 5.02 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL117 | CHRYSIN | — | 1 | 5.02 |
| CHEMBL275638 | FLAVONE | 2.0 | 1 | 4.68 |
| CHEMBL294009 | FLAVONOL | — | 1 | 4.38 |
| CHEMBL185 | FLUOROURACIL | 4.0 | 1 | 4.22 |
| CHEMBL399121 | HESPERETIN | 0.5 | 1 | 4.18 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL117 | CHRYSIN | IC50 | = | 9500.0 | nM | 5.02 |
| CHEMBL275638 | FLAVONE | IC50 | = | 21010.0 | nM | 4.68 |
| CHEMBL294009 | FLAVONOL | IC50 | = | 42100.0 | nM | 4.38 |
| CHEMBL185 | FLUOROURACIL | IC50 | = | 60000.0 | nM | 4.22 |
| CHEMBL399121 | HESPERETIN | IC50 | = | 66670.0 | nM | 4.18 |