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Assay Detail

CHEMBL4271289

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Functional
Growth inhibition of RAS-transformed human A549 cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type A549
Confidence 1 — Organism
Curated By Intermediate

Target

A549 (CHEMBL392)
Type CELL-LINE
Organism Homo sapiens

Publication

From bench (laboratory) to bed (hospital/home): How to explore effective natural and synthetic PAK1-blockers/longevity-promoters for cancer therapy.
Maruta H, Ahn MR.
Eur J Med Chem (2017) 142 : 229 -243
PubMed 28814374 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 6.00 6.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL299496 1 6.00
CHEMBL4293583 1 6.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL299496 IC50 = 1000.0 nM 6.00
CHEMBL4293583 IC50 = 1000.0 nM 6.00