Assay Detail
ADMET
CHEMBL4271576
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Cytotoxicity against human WISH cells assessed as decrease in cell viability after 48 hrs by MTT assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | WISH |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
New pyrazolopyridine analogs: Synthesis, antimicrobial, antiquorum-sensing and antitumor screening.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 4.50 | 5.09 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL53463 | DOXORUBICIN | 4.0 | 1 | 5.09 |
| CHEMBL4293981 | — | — | 1 | 4.67 |
| CHEMBL4289503 | — | — | 1 | 4.31 |
| CHEMBL4292895 | — | — | 1 | 4.29 |
| CHEMBL4290578 | — | — | 1 | 4.12 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL53463 | DOXORUBICIN | IC50 | = | 8140.0 | nM | 5.09 |
| CHEMBL4293981 | — | IC50 | = | 21590.0 | nM | 4.67 |
| CHEMBL4289503 | — | IC50 | = | 49020.0 | nM | 4.31 |
| CHEMBL4292895 | — | IC50 | = | 51170.0 | nM | 4.29 |
| CHEMBL4290578 | — | IC50 | = | 76360.0 | nM | 4.12 |