Assay Detail
Binding
CHEMBL4271577
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of methyl green from DNA (unknown origin) incubated in dark for 24 hrs
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Not specified |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
New pyrazolopyridine analogs: Synthesis, antimicrobial, antiquorum-sensing and antitumor screening.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 4.37 | 4.55 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4290578 | — | — | 1 | 4.55 |
| CHEMBL53463 | DOXORUBICIN | 4.0 | 1 | 4.50 |
| CHEMBL4292895 | — | — | 1 | 4.47 |
| CHEMBL4289503 | — | — | 1 | 4.43 |
| CHEMBL4282699 | — | — | 1 | 4.38 |
| CHEMBL4293981 | — | — | 1 | 4.25 |
| CHEMBL4282300 | — | — | 1 | 4.17 |
| CHEMBL4286075 | — | — | 1 | 4.17 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4290578 | — | IC50 | = | 28020.0 | nM | 4.55 |
| CHEMBL53463 | DOXORUBICIN | IC50 | = | 31270.0 | nM | 4.50 |
| CHEMBL4292895 | — | IC50 | = | 33980.0 | nM | 4.47 |
| CHEMBL4289503 | — | IC50 | = | 36710.0 | nM | 4.43 |
| CHEMBL4282699 | — | IC50 | = | 41710.0 | nM | 4.38 |
| CHEMBL4293981 | — | IC50 | = | 56400.0 | nM | 4.25 |
| CHEMBL4282300 | — | IC50 | = | 68150.0 | nM | 4.17 |
| CHEMBL4286075 | — | IC50 | = | 67830.0 | nM | 4.17 |