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Assay Detail

CHEMBL4272397

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of collagen prolyl 4-hydroxylase (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Collagen Prolyl 4-Hydroxylase as a Therapeutic Target.
Vasta JD, Raines RT.
J Med Chem (2018) 61 : 10403 -10411
PubMed 29986141 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 5.74 6.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL167301 1 6.00
CHEMBL166568 1 5.96
CHEMBL88972 PYRIDINE-2,5-DICARBOXYLIC ACID 1 5.26

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL167301 IC50 = 1000.0 nM 6.00
CHEMBL166568 IC50 = 1100.0 nM 5.96
CHEMBL88972 PYRIDINE-2,5-DICARBOXYLIC ACID IC50 = 5500.0 nM 5.26