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Assay Detail

CHEMBL4273852

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Functional
Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type A549
Confidence 1 — Organism
Curated By Intermediate

Target

A549 (CHEMBL392)
Type CELL-LINE
Organism Homo sapiens

Publication

Diterpenoid lead stevioside and its hydrolysis products steviol and isosteviol: Biological activity and structural modification.
Wang M, Li H, Xu F, Gao X, Li J, Xu S, Zhang D, Wu X, Xu J, Hua H, Li D.
Eur J Med Chem (2018) 156 : 885 -906
PubMed 30059803 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.20 5.39

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4286286 1 5.39
CHEMBL4279017 1 5.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4286286 IC50 = 4100.0 nM 5.39
CHEMBL4279017 IC50 = 9950.0 nM 5.00