Assay Detail
Functional
CHEMBL4275664
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Antiproliferative activity against human MCF7 cells assessed as reduction in cell growth after 72 hrs by sulforhodamine B assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MCF7 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
5'-Chloro-2,2'-dihydroxychalcone and related flavanoids as treatments for prostate cancer.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.03 | 5.31 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2297673 | — | — | 1 | 5.31 |
| CHEMBL428647 | PACLITAXEL | 4.0 | 1 | 4.94 |
| CHEMBL4283232 | — | — | 1 | 4.85 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2297673 | — | IC50 | = | 4900.0 | nM | 5.31 |
| CHEMBL428647 | PACLITAXEL | IC50 | = | 11500.0 | nM | 4.94 |
| CHEMBL4283232 | — | IC50 | = | 14100.0 | nM | 4.85 |