Assay Detail
Functional
CHEMBL4276052
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Antiproliferative activity against human SW480 cells after 72 hrs by colorimetric MTS assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | SW480 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Identification of DK419, a potent inhibitor of Wnt/β-catenin signaling and colorectal cancer growth.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.25 | 6.48 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL588564 | — | — | 1 | 6.48 |
| CHEMBL1448 | NICLOSAMIDE | 4.0 | 1 | 6.01 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL588564 | — | IC50 | = | 330.0 | nM | 6.48 |
| CHEMBL1448 | NICLOSAMIDE | IC50 | = | 980.0 | nM | 6.01 |