Assay Detail
Binding
CHEMBL4276649
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to CCKB receptor (unknown origin) expressed in HEK cells after 4 hrs by RP-LC-ICPMS analysis
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Gastrin/cholecystokinin type B receptor (CHEMBL298) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Receptor-Ligand Interaction Measured by Inductively Coupled Plasma Mass Spectrometry and Selenium Labeling.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 3 | 7.51 | 7.66 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL120632 | TETRAGASTRIN | -1.0 | 1 | 7.66 |
| CHEMBL4278080 | — | — | 1 | 7.53 |
| CHEMBL4286411 | — | — | 1 | 7.34 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL120632 | TETRAGASTRIN | Kd | = | 21.7 | nM | 7.66 |
| CHEMBL4278080 | — | Kd | = | 29.3 | nM | 7.53 |
| CHEMBL4286411 | — | Kd | = | 45.5 | nM | 7.34 |