Assay Detail
Binding
CHEMBL4303095
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Activity of compound against Alpha-2A (ADRA2A) adrenergic receptor by displacement of [3H]-rauwolscine
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
A SARS-CoV-2 protein interaction map reveals targets for drug repurposing
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 5.64 | 6.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1626 | CLEMASTINE | 4.0 | 1 | 6.77 |
| CHEMBL53325 | — | — | 1 | 5.82 |
| CHEMBL76 | CHLOROQUINE | 4.0 | 1 | 5.36 |
| CHEMBL1535 | HYDROXYCHLOROQUINE | 4.0 | 1 | 5.19 |
| CHEMBL4088272 | — | — | 1 | 5.08 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1626 | CLEMASTINE | Ki | = | 169.82 | nM | 6.77 |
| CHEMBL53325 | — | Ki | = | 1513.56 | nM | 5.82 |
| CHEMBL76 | CHLOROQUINE | Ki | = | 4365.16 | nM | 5.36 |
| CHEMBL1535 | HYDROXYCHLOROQUINE | Ki | = | 6456.54 | nM | 5.19 |
| CHEMBL4088272 | — | Ki | = | 8317.64 | nM | 5.08 |