Assay Detail
Binding
CHEMBL4305236
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human ERG expressed in CHOK1 cells by Q-patch electrophysiology method
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Voltage-gated inwardly rectifying potassium channel KCNH2 (CHEMBL240) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Anti-metastatic Inhibitors of Lysyl Oxidase (LOX): Design and Structure-Activity Relationships.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.70 | 5.34 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4564517 | — | — | 1 | 5.34 |
| CHEMBL4441173 | — | — | 1 | 4.60 |
| CHEMBL4434955 | — | — | 1 | 4.17 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4564517 | — | IC50 | = | 4600.0 | nM | 5.34 |
| CHEMBL4441173 | — | IC50 | = | 25000.0 | nM | 4.60 |
| CHEMBL4434955 | — | IC50 | = | 68000.0 | nM | 4.17 |