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Assay Detail

CHEMBL4305680

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of rat intestinal maltase-glucoamylase using p-nitrophenyl alpha-D-glucoside as substrate preincubated for 5 mins followed by substrate addition and measured after 30 mins
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Rattus norvegicus
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Synthetic heterocyclic candidates as promising α-glucosidase inhibitors: An overview.
Dhameja M, Gupta P.
Eur J Med Chem (2019) 176 : 343 -377
PubMed 31112894 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.40 7.40

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4448264 1 7.40

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4448264 IC50 = 40.0 nM 7.40