Assay Detail
Functional
CHEMBL4308946
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Mitochondrial uncoupling activity in mouse liver mitochondria assessed as effect on succinoxldase coupled phosphorylation
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Tissue | Liver |
| Subcellular | Mitochondria |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Small Molecule Mitochondrial Uncouplers and Their Therapeutic Potential.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 7.20 | 7.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL457504 | — | — | 1 | 7.40 |
| CHEMBL224214 | CARBONYL CYANIDE M-CHLOROPHENYLHYDRAZONE | — | 1 | 7.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL457504 | — | EC50 | = | 40.0 | nM | 7.40 |
| CHEMBL224214 | CARBONYL CYANIDE M-CHLOROPHENYLHYDRAZONE | EC50 | = | 100.0 | nM | 7.00 |